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Sanger Poster Session
March 2023
Well done Sophie and Phum on your excellent posters for the Sanger PhD poster session and congratulations Sophie on your poster prize!
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Sophie Hoffman joins the group
January 2023
Sophie is joining the group as a PhD rotation student. She will be focused on understanding transcriptomic changes in maternal immune cells during pregnancy.
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Christmas Lunch
December 2022
Great to celebrate all the achievements of the year over a delicious lunch.
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BBC Look East
November 2022
Emma discussed our recent work on stratifying patients with sepsis on BBC Look East.
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SepstratifieR
November 2022
Our method for stratifying patients with acute infections (sepsis, COVID-19 and flu) from transcriptomic data is now out at Science Translational Medicine. A great collaboration with all the GAinS investigators, led by Eddie Cano Gamez.
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Phumrapee Boonklang joins the group
October 2022
Phumrapee is joining the group as a Masters Student. He will be analysing bulk RNA-sequencing data collected from patients with melioidosis, the leading cause of sepsis in Thailand.
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ASHG
October 2022
Alex and Thomas are presenting their work on how genetic variants regulate gene expression through mechanisms such as alternative splicing and misexpression of a gene.
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Institute for Genomic Health Seminar Series, Mount Sinai
October 2022
Emma is presenting our work on understanding mechanisms of gene regulation in peripheral immune cells and their contribution to variation across individuals
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Lab retreat
September 2022
Fantastic day of scientific discussion and of course plenty of cake.
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LRA funding
August 2022
We’ve been awarded funding from the Lupus Research Alliance to investigate ancestry-specific molecular profiles in SLE patients. Very excited to work with our collaborators to further expand our SLE research in the group.
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Congratulations Nikhil!
August 2022
Nikhil has passed his MPhil viva. Now he’s off to Stanford to undertake a PhD.
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Christmas lunch
February 2022
Better late than never. Enjoying a belated Christmas lunch as a team
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Haerin Jang joins the group
January 2022
Haerin Jang is joining the group as a PhD rotation student. She will be analysing single cell RNA-seq data to further our understanding of the heterogeneity underlying SLE.
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UK Pharmacogenetics and Stratified Medicine Network
October 2021
Watch Emma Davenport present our work on eQTL interactions in sepsis
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Nikhil Milind joins the group
October 2021
Nikhil Milind is joining the group as a Churchill Scholar Masters Student. He will integrate genetic, transcriptomic, proteomic and epigenetic datasets to further our understandings of the molecular mechanisms underlying sepsis.
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Group away day
August 2021
Our first in person group meeting since March 2020! A great day discussing our research projects.
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Genomics Lite
March 2021
Watch Katie Burnham describe our research on variation across sepsis and why it is important
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Isaac Garcia Salinas joins the group
March 2021
Isaac Garcia Salinas is joining the group as a PhD rotation student. He will be working on identifying putative causal genes of neuropsychiatric lupus through genotype and brain gene expression data.
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Dhupal Patel joins the group
February 2021
Dhupal Patel is joining the group as a clinical PhD student. Dhupal is interested in investigating the impact of host genetics on inter-individual variation in the response to acute infection and sepsis.
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ELRIG's Drug Discovery Conference
October 2020
Katie Burnham is presenting our work on multi-omic approaches to investigate variation in the host sepsis response
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Thomas Vanderstichele joins the group
October 2020
Thomas Vanderstichele is joining the group as a PhD student. Thomas will be investigating how genetic variants and environmental factors influence the expression of immune-related genes.
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Sanger Seminar Series
September 2020
Emma presents an overview of the teams work in stratifying sepsis patients using transcriptomic profiling as part of the Sanger Seminar Series
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Niek de Klein joins the group
September 2020
Niek de Klein is joining the group as a Postdoctoral Fellow. Niek will be focusing on single cell transriptomics of lupus patients.
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Cambridge University Genetics Society Interview Series
August 2020
Watch Emma’s discussion of her research interests and career with members of the Cambridge University Genetics Society.
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Alex Tokolyi joins the group
March 2020
Alex Tokolyi is joining the group as a PhD rotation student. Alex will be working on splicing analysis in the GAinS cohort.
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Sepsis and precision medicine: is it all in your genes?
February 2020
A great write-up from Alison Cranage of Emma’s talk at the AAAS 2020 annual meeting.
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AAAS 2020 annual meeting
February 2020
Emma is presenting a talk on personalised medicine and how we are working on stratifying patients with sepsis using transcriptomics.
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Olivia Edwards joins the group
January 2020
Olivia Edwards is joining the group as a PhD rotation student. Olivia will be working on gene expression analysis in the BioAID cohort.
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Christmas Lunch
December 2019
We had a great Christmas lunch celebrating the first year as a group.
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Pager Podcast
December 2019
Emma chatted with George Milner about personalised medicine and what it could mean for the treatment of sepsis.
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Wanseon Lee joins the group
October 2019
Wanseon Lee is joining the group as a senior staff scientist. Wanseon will be working on the expression of genes in the MHC across individuals, populations and diseases.
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Stephanie McGimpsey joins the group
October 2019
Stephanie McGimpsey is joining the group as a PhD rotation student. Stephanie will be working on eQTL mapping in the BioAID cohort.
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Lab punting trip
July 2019
We survived the summer heat with a punting trip along the River Cam to the beautiful Grantchester Meadows.
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Sherry (Xiaoyun) Li joins the group
July 2019
Sherry Li is joining the group as a summer student. Sherry will be analysing genotyping and gene expression data for patients that present to the emergency room with suspected infection.
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BBC News article on personalised medicine
July 2019
Emma’s article has been published by the BBC: What does personalised medicine mean for you? Emma summarises some of the exciting advances in research that could allow treatments to be better tailored for individuals.
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Emma is presenting at CafeSci
April 2019
On 10th April come hear about our work on using genetics to understand why people respond in different ways to treatments.
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Open Targets Funding
March 2019
We’ve been awarded funding to map single cell expression quantitative trait loci (sceQTLs) in peripheral blood mononuclear cells isolated from healthy individuals (stimulated in vivo with different antigens) and patients with systemic lupus erythematosus. We aim to accelerate drug discovery by integrating immune disease GWAS variants with the sceQTLs to identify the most promising therapeutic targets. We’re looking forward to working with the Trynka team, clinical collaborators and the Open Targets partners on this exciting project!
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Katie Burnham joins the group
February 2019
Katie is joining the group as a postdoctoral fellow. Katie will work on investigating variation in the host immune response and its potential relevance in clinical decision making and drug development.
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Elena Cibrian Uhalte joins the group
January 2019
Elena is joining the group as a Janet Thornton postdoctoral fellow. Elena will be combining her expertise in molecular and cellular biology with -omics analysis to study how individual variants contribute to disease susceptibility and progression.
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Emma joins the Wellcome Sanger Institute
October 2018
Emma is starting the group in the Human Genetics Programme at the Wellcome Sanger Institute. Emma focuses on integrating functional genomics and clinical data in order to understand how genetics contributes to patient variation in disease severity and treatment response.
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ATS 2018
May 2018
Emma will be presenting a talk on transcriptomic Sepsis Response Signatures and eQTL interactions at the American Thoracic Society conference in San Diego.
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The Davenport Lab will be starting at the Wellcome Sanger Institute in October 2018
April 2018
The group will be joining the Human Genetics Programme at the Sanger Institute, UK. We will be building up a team to investigate the response to drug treatment in patients with inflammatory diseases using RNA-sequencing to profile gene expression in the blood.